Description: Aceglutamide and Sodium Chloride Injection is the treatment of comas due to traumatic brain injury and neurological surgery ,liver coma and hemiplegia, high paraplegia, polio sequelae, headache and low back pain. Aceglutamide is the main ingredient of Aceglutamide and Sodium Chloride Injection. Aceglutamide is a psychostimulant and nootropic used to improve memory and concentration. Chemically, it is the acetyl derivative of the amino acid L-glutamine. Aceglutamide can also be used as a liquid-stable source of glutamine to prevent damage from protein energy malnutrition.
Pharmacokinetics: Aceglutamide are present in high concentration In the brain, liver and kidney in high concentration which was widespreading in vivo. Also it can through the blood-cerebrospinal fluid (CSF) barrier. It will changed to N-acetylglutamateN- which will be involed in metabolism translation through disintegrate Ammonia in the uriniferous tubules treg. Then ammonia will be secreted and expelled through uriniferous tubules.
Indications: treatment of comas due to traumatic brain injury and neurological surgery ,liver coma and hemiplegia, high paraplegia, polio sequelae, headache and low back pain.