Description: Oxaliplatin is the third generation of platinum agents, which is a landmark product of platinum anticancer drugs. This product is the first-line drug of the gastrointestinal antitumor. It joined the mannitol as solvent can be directly intravenous drip without preparation when large capacity injection dosage use in clinical. Oxaliplatin and Mannitol Injection can significantly reduce the patients with renal toxicity of platinum agents. It is indicated for adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the primary tumor. And for the treatment of advanced colorectal cancer. Its chemical name is [(1R,2R) -cyclohexane -1,2-diamine] (ethanedioato-O,O')platinum(II)
Indications: Oxaliplatin and Mannitol Injection is indicated for: adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the primary tumor.And for the treatment of advanced colorectal cancer.
Adverse reaction: The most common adverse reactions in patients with stage II or III colon cancer receiving adjuvant therapy were peripheral sensory neuropathy, neutropenia, thrombocytopenia, anemia, nausea, increase in transaminases and alkaline phosphatase, diarrhea, emesis, fatigue and stomatitis. aaa